Friday, November 29, 2019

Sustainability Ethical and Social Responsibility Dimensions Sample Essay Example For Students

Sustainability: Ethical and Social Responsibility Dimensions Sample Essay When doing concern determinations that impact the environment. there are frequently hazards and issues that affect an organisation. It is of import to place those issues and hazards to advance sustainability. Stakeholders have concerns about different facets of the environment and how organisations should react to them through schemes and how they operate. A positive ethical civilization can be created when a concern shows concern for the environment. Harmonizing to Ferrell. Fraedrich and Ferrell ( 2011 ) â€Å"corporate societal duty public presentation has been found to increase employee’s company designation and commitment† ( p. A-2 ) . Essential Facts We will write a custom essay on Sustainability: Ethical and Social Responsibility Dimensions Sample specifically for you for only $16.38 $13.9/page Order now A major issue in the 21st century is the protection of our natural resources such as air. H2O. land. biodiversity. and renewable natural resources. Governments around the universe have responded to force per unit areas put on the sustainability of these resources by environmental protection Torahs. Companies have been progressively integrating these issues into their concern schemes to non merely cut down their ain environmental impact. but to make a repute as eco-responsible companies. Issues Raised Air pollution can harm animate beings. workss and organic structures of H2O. There is a significant sum of pollution that comes from semisynthetic beginnings such as from mills. autos. planes and trains that have an consequence on the quality of air we breathe. These conditions can cut down life spans and do chronic respiratory issues in animate beings and worlds. Some of the chemicals that are associated with air pollution have been known to lend to deliver defects. malignant neoplastic disease and other amendss to the human organic structure. Harmonizing to Ferrell. Fraedrich and Ferrell ( 2011 ) pollution can â€Å"also cause haze. which can cut down visibleness and interfere with traveling† ( p. A-2 ) . Global heating is believed by scientists to be accelerated by the concentrations of green house gases like methane and C dioxide in the ambiance. Burning of fossil fuels?gasoline. oil. natural gas and coal. has increased the concentrations of these nursery gases into the am biance. Water pollution affects one million millions of people every bit good as other animate beings and works life. Ferrell. Fraedrich and Ferrell ( 2011 ) province â€Å"water pollution is one of the biggest subscribers to illness in developing countries† ( p. A-3 ) . The chemicals that are found in common fertilisers and pesticides can run out into H2O supplies after a rainfall. Pollutants can come from a broad assortment of beginnings including from C emanations from autos that are absorbed into the ocean. Dumping of waste into our watercourses. rivers and oceans. every bit good as oil spills. industrial waste. and more contribute to the issue of H2O pollution. Water measure is besides a concern by many people due to the usage addition over the last two decennaries. Water is non merely needed to imbibe. it is besides used for harvests that feed us all. With less H2O available. nutrient harvests will non be as available. and concerns may endure because of it. Ferrell. Fraedrich and Ferrell ( 2011 ) province â€Å"one of the biggest factors in land pollution is the dumping of waste into landfills. † and landfills that are left untreated can take 1. 000 old ages to degrade. The U. S. entirely has up to 40. 000 abandoned landfills filled with plastics and other points like electronic waste that can let go of harmful toxins into the air and H2O ( p. A-4 ) . Deforestation is been on the rise because of the roar in bio-fuels. Trees are being cut down to do room for palm oil plantations or for raising sugar cane. Harmonizing to Ferrell. Fraedrich and Ferrell ( 2011 ) â€Å"the net incomes from deforestation for husbandmans are normally ephemeral as rainforest dirt is of hapless quality. This prompts low-income husbandmans to destruct more forest to eke out a living† ( p. A-4 ) . After World War II edifice roar. urban conurbation began. Ferrell. Fraedrich and Ferrell ( 2011 ) province â€Å" As the topographic points where people live. work. and store grew farther apart. peoples began passing more clip in cars driving greater distances† ( p. A-5 ) . This has non merely contributed to devour wildlife home grounds. wetlands. and farming area. it has besides contributed to air. H2O. and land pollution. Ferrell. Fraedrich and Ferrell ( 2011 ) say that â€Å"deforestation. pollution. development. and urban conurbations have put increasing force per unit area on wildlife. workss and their habitats† ( p. A-5 ) . Many workss and animate beings have already become nonextant. and th ere are 1000s more threatened. Experts fear that the overexploitation of natural resources will do ruinous instabilities in the environment. Harmonizing to Ferrell. Fraedrich and Ferrell ( 2011 ) â€Å"each biological species plays a alone function in its ecosystem and is portion of a complex concatenation of events. the loss of any one of them may endanger the full ecosystem† ( p. A-5 ) . Analysis of Decision / Final Consequence .uae904cbcae8cd4c4d5e55f30877eb654 , .uae904cbcae8cd4c4d5e55f30877eb654 .postImageUrl , .uae904cbcae8cd4c4d5e55f30877eb654 .centered-text-area { min-height: 80px; position: relative; } .uae904cbcae8cd4c4d5e55f30877eb654 , .uae904cbcae8cd4c4d5e55f30877eb654:hover , .uae904cbcae8cd4c4d5e55f30877eb654:visited , .uae904cbcae8cd4c4d5e55f30877eb654:active { border:0!important; } .uae904cbcae8cd4c4d5e55f30877eb654 .clearfix:after { content: ""; display: table; clear: both; } .uae904cbcae8cd4c4d5e55f30877eb654 { display: block; transition: background-color 250ms; webkit-transition: background-color 250ms; width: 100%; opacity: 1; transition: opacity 250ms; webkit-transition: opacity 250ms; background-color: #95A5A6; } .uae904cbcae8cd4c4d5e55f30877eb654:active , .uae904cbcae8cd4c4d5e55f30877eb654:hover { opacity: 1; transition: opacity 250ms; webkit-transition: opacity 250ms; background-color: #2C3E50; } .uae904cbcae8cd4c4d5e55f30877eb654 .centered-text-area { width: 100%; position: relative ; } .uae904cbcae8cd4c4d5e55f30877eb654 .ctaText { border-bottom: 0 solid #fff; color: #2980B9; font-size: 16px; font-weight: bold; margin: 0; padding: 0; text-decoration: underline; } .uae904cbcae8cd4c4d5e55f30877eb654 .postTitle { color: #FFFFFF; font-size: 16px; font-weight: 600; margin: 0; padding: 0; width: 100%; } .uae904cbcae8cd4c4d5e55f30877eb654 .ctaButton { background-color: #7F8C8D!important; color: #2980B9; border: none; border-radius: 3px; box-shadow: none; font-size: 14px; font-weight: bold; line-height: 26px; moz-border-radius: 3px; text-align: center; text-decoration: none; text-shadow: none; width: 80px; min-height: 80px; background: url(https://artscolumbia.org/wp-content/plugins/intelly-related-posts/assets/images/simple-arrow.png)no-repeat; position: absolute; right: 0; top: 0; } .uae904cbcae8cd4c4d5e55f30877eb654:hover .ctaButton { background-color: #34495E!important; } .uae904cbcae8cd4c4d5e55f30877eb654 .centered-text { display: table; height: 80px; padding-left : 18px; top: 0; } .uae904cbcae8cd4c4d5e55f30877eb654 .uae904cbcae8cd4c4d5e55f30877eb654-content { display: table-cell; margin: 0; padding: 0; padding-right: 108px; position: relative; vertical-align: middle; width: 100%; } .uae904cbcae8cd4c4d5e55f30877eb654:after { content: ""; display: block; clear: both; } READ: Atomic Bomb EssayThere are several options to fossil fuels that can cut down pollutions and better the environment. Wind power. geothermic power. solar power. atomic power. bio-fuels and hydropower to call a few. Many organisations are larning that to be environmentally friendly and sustainable has many benefits? including stakeholder good will and money nest eggs from being more efficient and less uneconomical. There have been surveies that suggest that bettering a company’s environmental public presentation can increase grosss and cut down costs. Poor environmental direction has been recognized by Bankss who grant loans to be an increased hazard. Workers besides c are about the impact that their companies have on the environment. Ferrell. Fraedrich and Ferrell ( 2011 ) province â€Å"that reacting to stakeholders’ concerns about environmental issues will both better relationships with stakeholders and do the universe a better place† ( p. A-13 ) . Textbook Questions 1. The chief issue associating to sustainability in our society is the deficiency of ordinance globally in respects to pollution and waste direction. 2. I believe that solar power is the feasible beginning of alternate energy because it is 100 % renewable and can be stored in batteries. 3. I do non believe it is acceptable for companies to overstate environmental claims to sell merchandises. In making so it is non ethical. It is the same as stating portion of the truth. I believe companies should be held to high criterions and held accountable to them. Mentions Ferrell. O. C. . Fraedrich. J. . A ; Ferrell. L. ( 2011 ) . Business moralss: Ethical determination devising and instances. ( 9th erectile dysfunction. . Vol. erectile dysfunction. ) . Mason. Ohio: South-Western Cengage Learning.

Monday, November 25, 2019

To Kill Mockingbird essays

To Kill Mockingbird essays One theme of the novel To Kill A Mockingbird is the transition from innocence to experience. At the beginning of the story To Kill A Mockingbird Scouts world is limited to the boundaries of immediate neighborhood. She feels safe and secure, and totally confident that the way things are done in her home is not just the right way, but also the only way. The arrival of Dill, who comes from a broken home and has lived in another state, gives Scout her first hint of a variety of many experiences beyond her narrow horizons. Then, Scouts first day of school in Maycomb is not necessarily correct. She also learns that sometimes it is necessary to compromise in order to get along. Even though Scouts teachers ideas about how to teach reading may be wrong, Scout must respect her teachers authority. Her own father advises her to ignore the teachers ban on reading at home, but to pretend to go along with the teachers methods in the classroom. This kind of social hypocrisy is new to Scout, and sh e is surprised to hear her very own moral father Atticus advocating it. As the story progresses, Scout encounters other numerous examples of the complexity of human motivation. Sometimes characters that do evil things, such as Mayella Ewell, are nevertheless more pitiful than hateful. On the other hand, it is possible for some individuals to do the right thing for quite unexpected reasons. Mr. Underwood does not like blacks and is a mean-spirited person in general, yet he alone helps Atticus during the quarrel at the jail. By the final chapters of the novel, Scout has learned that good and justice do not necessarily triumph every time. Harmless individuals such as Tom Robinson and Boo Radley can become victims through no fault of their own. Sometimes the system can do nothing to defend them. In one of the final scenes of the story, the sheriff puts compassion ahead of the letter of the law so th...

Friday, November 22, 2019

Understanding markets Essay Example | Topics and Well Written Essays - 2000 words

Understanding markets - Essay Example Using different methods, Marketing determines the size of the market that is being approached but this has to be a controlled exercise otherwise the effort will be aimless. Marketing is a highly misunderstood word. It is not tactics or methods of getting customers to buy a company’s product or services. That is advertisement or promotions. It is a conscious effort to analyze and understand what is needed and trying to fulfill this need. But above all, Marketing is all about customers. Their behavior and attitude towards buying a product is of paramount importance. Their needs and wants and their likes and dislikes are decisive factors and purchase decisions depend on these issues. It is the understanding of these factors that will develop a marketing strategy. Therefore Marketing is all about understanding the customers and of finding ways and means to for providing product or service as per his requirements. â€Å"Marketing is an organizational function and a set of processes for creating, communicating and delivering value to customers and for managing customer relationships in ways that benefit the organization and its stakeholders†. (AMA). This comprehensively calls for Market segmentation and results in two way satisfaction of both customer and the stakeholder. Markets are heterogeneous and are created by reasons of different values, needs wants, constraints, beliefs and incentives. Customers differ in their values and perceptions and want to purchase things that have value for them. Value is not just the monetary part, but also the usefulness and emotions that with go with it. The need and want play a great role in determining this value. The price actually determines the location from which this purchase will be made. Service and reliability are other important determining factors. Therefore a market segment is a set of customers that have a common approach to above questions and have a common desire to purchase a common set of goods and or services.

Wednesday, November 20, 2019

Discuss the role played by morality or obligation in Antigone Essay - 1

Discuss the role played by morality or obligation in Antigone - Essay Example Both assertions are legitimate and are present in an unavoidable tension. Another probability is to interpret the play as a mere justification of Antigone over Creon, as an absolution of the individual’s appreciation of right and wrong over the assertions of the state and nothing more. In the story Antigone, the literary style of tragedy is accentuated by the arrangement of the events from order to chaos. The two central characters in the story were the tragic heroine Antigone and pragmatic but weary ruler Creon. Both Antigone and Creon primarily played significant roles in the story; yet, the former one was the character who brought about relevant changes in the kingdom through her insistence of personal desire. The death of Antigone became the glaring signal of the sudden demise of the central characters of the story such as Haemon, the fiancà © of Antigone, and Eurydice, the knitting wife of Creon. The suicides of Haemon and Eurydice were the last punishment bestowed upon Creon. Antigone was a headstrong and unruly heroine at first but then after her failure to bury his brother’s body, Polynices who died in the battle for the throne, she underwent an internal change that is manifested in her utter rejection of the desire to live longer and happily with her love Haemon. She courageously accepted the punishment of execution for her acts which consequently symbolized her solitary combat against state power. In her bold decision not to cede to Creon, Antigone’s beauty as a tragic heroine surfaced in the crucial moments of her hopelessness and misery. Ismene, her physically enticing sister, admitted that Antigone is beautiful in way that doesn’t please the eyes but in an unsettling, frightening and remarkable way. The activities of Antigone in the story resultantly affected the fate of the other characters. Creon, on the other hand, failed in his

Monday, November 18, 2019

Womens History Essay Example | Topics and Well Written Essays - 750 words

Womens History - Essay Example Constitution was ratified by the 19th Amendment giving women the right to vote. Formation of one group in 1890, National American Women Suffrage Association (NAWSA), Stanton being the president and the vice-president being Anthony was an effective strategy and vital policy to gain suffrage. The nonviolent approach was the suffragist’s logical strategy since Quakers and pacifists like Alice Paul, Lucretia Mott, and Susan B. Anthony who was its prominent leaders encouraged peaceful resistance in order to be equal with men. Another strategy that was used by the Suffrage Movement to outwit opponents was the involvement of professionals who had proved to be enormously competent, politically important, widely respected and highly influential like Elizabeth Cady Stanton, Susan B. Anthony, Lucy Stone, Carrie Chapman Catt, Harriet Stanton Blatch, and Alice Paul. Vigorous campaigning was another major input which gave the movement victory in the long run after over 72 years of campaigni ng and pooling of resources to fund it. The campaigns were filled with commitment, intrigue, dedication, and frustration. Millions of dollars were pooled as hundreds gave such aid wherever and whenever they could together with constant interest. Hundreds of women gave possibilities of an entire lifetime. Enlisting of new members also proved to be above par policy and strategy in order to popularize the movement. The inclusion of men was another strategy as men had vital roles in casting votes that could only be cast by men. The 19th Amendment was approved by virtually all-male Senate and House and ratified by 36 all-male, virtually, legislatures.Though the movement fought for the women’s rights, it is regarded in some quarters as a cause that was inconsequential worth neither of respect nor attention.  

Saturday, November 16, 2019

Propylene Glycol as a Pharmaceutical Excipient in Pediatrics

Propylene Glycol as a Pharmaceutical Excipient in Pediatrics Disha Patel The Utilization of Propylene Glycol as a Pharmaceutical Excipient in the Pediatric Field Abstract As a widely used excipient in pediatric formulations, propylene glycol functions as a solvent, emulsifier, humectant, and hygroscopic agent. It is a clear, colorless liquid whose properties enable it to have pharmacodynamic applications. Oftentimes, propylene glycol is combined with other mediations to enhance its penetration. For instance, a combination of 20% propylene glycol and 5% lactic acid in a semiocculusive cream base is used as a highly effective and well-tolerated keratolytic in patients with lamellar ichthyosis and possibly could be in various other hyperkeratotic diseases. Unfortunately, though to a lesser degree, this excipient is associated with toxic effects such as hyperosmolality, hemolysis, and lactic acidosis. Also, in concentrations greater than 10%, propylene glycol may act as an irritant in some patients (Health Effects 2). From a pharmacokinetic viewpoint, there is a potential of renal toxicity associated with propylene glycol and lorazepam. The high concentra tion of propylene glycol contained in certain intravenous drug products, such as phenytoin, diazepam, digoxin, and etomidate, may induce thrombophlebitis. Here, the patients increased serum creatinine concentrations are likely to have resulted from exposure to propylene glycol due to lorazepam infusion. Serum osmolality and osmol gap may be useful markers for propylene glycol toxicity. Much like the above mentioned applications, through its chemical composition, propylene glycol has the ability to exert a beneficial effect on pediatric formulations (Webbook 5). Introduction Propylene glycol, which is also known Propane-1,2-diol, is a colorless, viscous, organic liquid with a slightly sweet taste. This excipient is utilized in food, cosmetics and pharmaceutical preparations. Examples of pharmaceutical applications include therapeutic drugs such as vaccines, cough syrups, local anesthetics, antiseptics, vitamins, and hormones. It is produced through the fermentation of yeast and carbohydrates. Propylene glycol is industrially made from propylene oxide. It is made from either a catalytic or a non-catalytic method which exposes the propylene into extremes of temperature and a small amount of sulfuric acid or alkali to yield propylene glycol for industrial purposes (Frequently Asked Questions about Propylene Glycol 1). It is concluded that, with extensive research, this excipient is categorized as safe in the body. According to the Agency for Toxic Substances Disease Registry, in the body, under conditions of normal low exposure, propylene glycol is quickly metabolized and excreted. Its metabolic pathway is comparable to that of sugar: propylene glycol is quickly converted into lactic acid, similar to what happens with the energy in the muscles when exercising. Afterwards, the lactic acid is excreted via urine (Database of Select Committee on GRAS Substances (SCOGS) Reviews 2). Surprisingly, from a toxicological point of view, alcohol is more toxic than propylene glycol. Propylene glycol has been used safely for more than 50 years in a large variety of applications. As a result, it is effectively used in prescription medications such amoxicillin (500 mg), clindamycin hydrochloride (150 mg 300 mg), gabapentin (300 mg), lyrica (50 g 75 mg), and omeprazole (20 mg) (Result Filters 4). Through statistical data, it is overwhelmingly evident that there is a continually growing market for propylene glycol. According to the IHS website, United States (19%), Western Europe (39%), Japan (17%), and China (80%) had the largest consumption (Inactive Ingredients in Pharmaceutical Products 5). Since it has been proven safe with a relative low toxicity level, it is projected that the consumption of propylene glycol will rise (IHS Home Page 4). The Effects of Propylene Glycol in Pediatrics Pharmaceutical medications are composed of two very essential ingredients: active pharmaceutical ingredients (APIs) and excipients. The purpose of the active pharmaceutical ingredient in a drug is to elicit a specific therapeutic effect on the patient. Specifically, when the drug is consumed, it will exert a necessary effect on the body in order to produce an ideal outcome: the therapeutic response (TOXICOLOGICAL PROFILE FOR PROPYLENE GLYCOL 3). The component of the drug is the excipient, which is an inactive ingredient utilized for possible multifunctional usage. For instance, an excipient can be binders, coatings, diluents, disintegrants, fillers, flavors, colors, lubricants, glidants, sorbents, preservatives, sweeteners, and solubilizing agents. Oftentimes, they do acquire some extent of therapeutic acclivity, though less than the API. Similar to many other drugs, propylene glycol functions both, as an API and excipient-an indication that multiple functions can have multiple benef its (AccessMedicine [41168448] 2). Additionally, medications are tailored to a specific age group to maximize the therapeutic effect for the patient. Therefore, criteria for an ideal drug for the pediatric population will undoubtedly differ from the criteria for the geriatric population. Routes of administration suitable for pediatrics include oral, topical, rectal, inhalation, injectable and drop (eye, ear, and nose). Propylene glycol enters the body as an alcohol and metabolizes in the bodys enzyme pathways. These pathways do not mature in humans until 12 to 30 months of age. Proper judgment when administering a propylene glycol-based formulation to neonates is crucial in order to prevent potential complications (PubChem 1). In comparison to adults, new born babies have a propylene glycol half-life of 16.9 hours rather than a significantly lower 5 hour half-life for adults. In one study, the use a multivitamins whose contents included propylene glycol resulted in serum osmolality in low-birth-weight premature babies. However, in another research activity, phenobarbital injections containing propylene glycol were deemed to have an inconsequential effect on the osmolar gap (AccessMedicine [40400741] 4). A higher amount of propylene glycol delivered per dose, such as 3 grams, is known to cause more seizures in infants, in comparison to those receiving lesser amounts per dose, such as 300 mg. In a population of 262 patients treated for burns, roughly 3 percent were the result of topical propylene glycol which resulted in hyperosmolality (Potential Safety Concerns with the Large Amount of Propylene Glycol 2). Since propylene glycol is a liquid excipient, it affects the gastrointestinal tract. However, studies of people and animals show that if you have repeated eye, skin, nasal, or oral exposures to propylene glycol for a short time, you may develop some irritation. Furthermore, extensive studies performed have concluded that there are no severe risks of propylene glycol in infants. Thus, it is assumed to be safe if consumed in moderation. The oral liquid formulation also illustrates a high compliance rate amongst infants. Simple considerations such as route of administration and effective concentrations can help achieve a therapeutic response (AccessMedicine [40400741] 6). The chemical composition of propylene glycol is relatively simple: alcohol groups with a hydrocarbon backbone. To an extent, this simplistic structure plays a broad role in various applications ranging from industrial to pharmaceutical uses. Generally, neonates can be exposed to propylene glycol orally or topically. Absorption through oral intake is significantly more effective than on the skin. Once propylene glycol reaches the site of action, it is rapidly metabolized and subsequently excreted (A-Z Index 9). In the blood stream, the half-life of the excipient is approximately 2-4 hours in adults. However, in neonates, it is drastically longer (17 hours). Pertaining to its mechanism of action, it is further metabolized to lactate which is further metabolized to pyruvate, carbon dioxide, and water. Through utilization of the gluconeogenic pathway, glucose is formed. Even though the safety the propylene is apparent, extremely large exposures to propylene glycol have the potential to r esult in lactic acidosis and hyperosmotic changes in the blood (Health Effects 4). Extensive research has provided sufficient evidence on the safety and quality of this excipient. To begin, numerous sources indicate that propylene glycol has a dramatically low degree of toxicity. It is associated with moderately low concern for acute toxicity by ingestion, skin contact, and inhalation. There have been reports of altered nervous system function because of high oral exposure to propylene. Normal metabolism of this excipient can be negatively affected through blood pH and osmotic changes. Furthermore, animal studies also confirm the relative low risk of propylene glycol (Webbook 2). For example, a longitudinal study performed on rodents with extremely high exposures to the excipient presented no indication of adverse effects. Consequently, a similar study performed on cats illustrated hematological changes. High aerosol concentrations inhaled by rats caused minor nasal and ocular signs that may have been due to mild irritation or drying effects of propylene glycol on mucous membranes. On a positive note, there is no correlation to cancer from the use of propylene glycol (AccessMedicine [45774923] 1). Pharmacological Profile of Propylene Glycol Propylene glycol, with a formula C3H8O2, is readily miscible with water, acetone, and chloroform. In reference to its structure, it contains an asymmetrical carbon atom, so it has two enantiomers. Since the commercial product is a racemic mixture, pure optical enantiomers can be achieved by the hydration of optically pure propylene oxide. Upon the mixture of propylene glycol and water, the freezing point of water is drastically depressed. Because of this, it is used as a de-icing fluid for vehicles. With the exception of ethylene glycol, glycols are generally known to be non-corrosive and have low volatility and toxicity. Even with the strict criteria established for pediatrics, propylene glycol satisfies the requirements for safe administration to pediatric patients (A-Z Index 5). Furthermore, it is derived from propylene oxide and its production methods include either catalytic- proceeds at 150  °C to 180  °C in the presence of ion exchange resin or a small amount of sulfuric acid or alkali, or non-catalytic- high-temperature process at 200  °C to 220  °C (IHS Home Page 3). Even though this paper focuses mainly on propylene glycol’s purpose as an excipient in pediatric formulations, it has an overwhelmingly degree of other applications. A certain amount (45%) is used as chemical feedback for the manufacture of unsaturated polyester resins. Chemically speaking, propylene glycol reacts with a mixture of unsaturated maleic anhydride and isophthalic acid to give a copolymer. Continuing further crosslinking, thermoset plastics are produced from the unsaturated polymers. Similarly, propylene glycol also reacts with propylene oxide to produce oligomers as well as polymers that are utilized to form polyurethanes (Frequently Asked Questions about Propylene Glycol 2). As proven be multiple research articles, this excipient is proven safe. The extent of safety is measured by plasma concentration: â€Å"Serious toxicity generally occurs only at plasma concentrations over 1 g/L, which requires extremely high intake over a relatively short period of time.† However, there is always an uncertainty and accidental occurrences. For instance, rare cases of propylene glycol poison were largely related to either inappropriate intravenous administration or accidental ingestion of enormously large quantities by children (Hazardous Substance Fact Sheet 9). Conclusion As proven through this research paper, propylene glycol is an effective ingredient for pediatric use. Since there was no established linkage between cancer and its use, it is popular for multiple uses. Several considerations should be utilized in formulating pediatric medications-specifically, the ingredients in the formulation. With its multiple uses, propylene glycol is well-suited for children for its safety and effectiveness. Like all ingredients, propylene glycol may produce adverse effects in the patient, but drastically less harmful than others. Since an enormous quantity must be consumed before toxicity level is reached, it is well suited for children. With viscous properties, upon consumption, it has the potential to elicit a faster therapeutic effect on the patient. Therefore, it is both potent and efficacious. In all, this ingredient proves to be a significant element to the overall formulation of a medication, regardless of the age group targeted (Webbook 5). Bibliography A-Z Index. ATSDR. N.p., n.d. Web. 13 Apr. 2014. http://www.atsdr.cdc.gov/phs/phs.asp?id=1120tid=240>. Database of Select Committee on GRAS Substances (SCOGS) Reviews. AccessData. N.p., n.d. Web. 13 Apr. 2014. http://www.accessdata.fda.gov/scripts/fcn/fcnDetailNavigation.cfm?rpt=scogsListingid=262>. Frequently Asked Questions about Propylene Glycol. N.p., n.d. Web. 13 Apr. 2014. http://www.propylene-glycol.com/uploads/PropyleneGlycolAdvocacybrochure.pdf>. Hazardous Substance Fact Sheet. New Jersey Department of Health. N.p., n.d. Web. 13 Apr. 2014. http://nj.gov/health/eoh/rtkweb/documents/fs/3595.pdf>. Health Effects. ATSDR. N.p., n.d. Web. 13 Apr. 2014. http://www.atsdr.cdc.gov/ToxProfiles/tp189-c2.pdf>. InactiveIngredients in Pharmaceutical Products: Update (Subject Review). Peditrics. N.p., n.d. Web. 13 Apr. 2014. http://pediatrics.aappublications.org/content/99/2/268.full#sec-11>. Potential Safety Concerns with the Large Amount of Propylene Glycol. Natap. N.p., n.d. Web. 13 Apr. 2014. http://www.natap.org/2000/may/potential_safety051500.htm>. Propylene Glycol. PubChem. N.p., n.d. Web. 13 Apr. 2014. http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=1030>. Propylene Glycol. Webbook. N.p., n.d. Web. 13 Apr. 2014. http://webbook.nist.gov/cgi/cbook.cgi?ID=C57556Mask=8>. Propylene Glycols. IHS Home Page. N.p., n.d. Web. 13 Apr. 2014. http://www.ihs.com/products/chemical/planning/ceh/propylene-glycols.aspx>. Result Filters. National Center for Biotechnology Information. U.S. National Library of Medicine, n.d. Web. 13 Apr. 2014. http://www.ncbi.nlm.nih.gov/pubmed/14524641>. St. Johns University Academics Schools Libraries. AccessMedicine. N.p., n.d. Web. 13 Apr. 2014. http://accessmedicine.mhmedical.com.jerome.stjohns.edu/content.aspx?bookid=348sectionid=40381672jumpsectionID=40400741>. St. Johns University Academics Schools Libraries. AccessMedicine. N.p., n.d. Web. 13 Apr. 2014. http://accessmedicine.mhmedical.com.jerome.stjohns.edu/content.aspx?bookid=388sectionid=45764289jumpsectionID=45774923>. St. Johns University Academics Schools Libraries. AccessMedicine. N.p., n.d. Web. 13 Apr. 2014. http://accessmedicine.mhmedical.com.jerome.stjohns.edu/content.aspx?bookid=392sectionid=41138958jumpsectionID=41168448>. TOXICOLOGICAL PROFILE FOR PROPYLENE GLYCOL. Agency for Toxic Substances and Disease Registry. N.p., n.d. Web. 13 Apr. 2014. http://www.atsdr.cdc.gov/toxprofiles/tp189.pdf>.

Wednesday, November 13, 2019

Charles Franklin Kettering :: essays research papers

Charles Franklin Kettering Charles F. Kettering : Doing the right thing at the right time By Richard P. Scharchburg, Thompson Professor of Industrial History The Man... Charles Franklin Kettering was born on a farm near Loundonville, Ohio, August 29, 1876. After graduation from high school, he accepted a teaching position in a one-room rural school. Although highly successful as a teacher, his mind was set on going to college. In the summer of 1896, he entered the College of Wooster (Ohio). As a result of long and intense hours of study, his eyesight deteriorated to the point that he was forced to leave college and return to teaching. In 1898, he entered the engineering school at Ohio State, but again his poor eyesight forced him to drop out during his freshman year. For the next two years he worked on a telephone line crew, and then once again entered Ohio State, finally completing his electrical engineering degree in 1904. After graduation, Kettering took a job in the inventions department at the National Cash Register Company (NCR) in Dayton, Ohio. There he developed an electric motor for cash registers, the OK Charge Phone for department stores and several other contributions to a revolution then taking place in business machines. In 1909, Kettering and Edward A. Deeds, his associate at NCR, formed their own industrial research laboratory, the Dayton Engineering Laboratories Company (later known as DELCO). Within three years, they had produced a new all-electric starting, ignition and lighting system for automobiles. The system first appeared as standard equipment on the 1912 Cadillac and as its use spread, women could conveniently become drivers without the assistance of a chauffeur. DELCO was eventually sold to General Motors and became the foundation for the General Motors Research Corporation of which Kettering became vice president in 1920. The list of innovations and inventions that are credited to Charles F. (nicknamed "Boss") Kettering is impressive. His book of patents contains more than 300 separate applications that range from a portable lighting system for farms to coolants for refrigerators and air conditioners. Other patents included a World War I "aerial torpedo," a device for the treatment of venereal disease, and an incubator for premature infants. Duco paint and Ethyl gasoline were also his ideas and he was instrumental in their development.